| 1980 |
Registration of Matrusri Education Society |
| 1981 |
Inauguration of the college by Sri T. Anjiah, Chief Minister, AP at temporary premises at Ameerpet, with an intake of 180 in Civil, ECE and Mechanical disciplines |
| 1983 |
Shifting of the college to Saidabad Campus |
| 1985 |
Starting of BE (CSE) Course |
| 1986 |
Inauguration of the Administrative block at Saidabad Campus by Sri P. V. Narasimha Rao, Minister of Human Resources, Govt. of India. |
| 1991 |
Decemal Celebrations; Award of Gold Medals to Class Toppers by MECT |
| 1992 |
Award of Gold Medals to Best Teachers by MECT |
| 1993 |
Permanent affiliation for Civil, Mech., ECE, and CSE by OU |
| 1994 |
Start of MCA Course |
| 1995 |
Foundation Stone of Science Block laid at Nadergul Campus by Sri M. Gopal Rao |
| 1997 |
Shifting of 1 year to Nadergul Campus, Introduction of BE (EEE) & MBA Courses |
| 2000 |
Shifting of all Engineering disciplines to Nadergul Campus, Start of BE (IT) Course |
| 2000 |
Formation of Matrusri Institute of PG Studies with MCA and MBA at the Saidabad Campus |
| 2001 |
Introduction of BE (Production) Course |
| 2002 |
Inauguration of Canteen and Physical Education Dept.Block |
| 2003 |
First AICTE (MODROBS) Grant received |
| 2004 |
Inauguration of CS & IT block by Sri V. Rama Rao, Governor of Sikkim |
| 2004 |
Construction of Bank building for the College |
| 2005 |
Start of first PG course M.E (CAD / CAM) in Mech. Engg. Dept. |
| 2006 |
Construction of 5,000 sqm area on II floor of Civil, Mechanical and CS & IT blocks |
| 2008 |
Introduction of MCA course |
| 2009 |
Introduction of MBA Course ; Introduction of BE (Automobile) Course |
| 2010 |
Introduction of ME (Embedded Systems & VLSI Design) |
| 2010 |
Introduction of M.Tech (CSE) |